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Turning the spotlight on cellular imaging

Advances in imaging are enabling researchers to track more accurately the localization of macromolecules in cells.

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Figure 1: A schematic illustrating the different approaches used in preparing water-soluble nanocrystals and to conjugate quantum dots to biomolecules.

© Bob Crimi

Figure 2: How molecular beacons operate. The molecular beacon has a quencher (blue circle) opposite a harvester fluorophore (green circle) when it is in a hairpin confirmation.

© Bob Crimi

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Mitchell, P. Turning the spotlight on cellular imaging. Nat Biotechnol 19, 1013–1017 (2001). https://doi.org/10.1038/nbt1101-1013

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