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From biomarkers to integrated network responses

The ability to quantify carbon fluxes in mammalian cells is a step toward elucidating the dynamic metabolic networks associated with health and disease.

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Figure 1: Interactions between molecular components give rise to metabolic network responses.

References

  1. Sauer, U. Mol. Syst. Biol. 2, 62 (2006).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Munger et al. Nat. Biotechnol. 26, 1179–1186 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Young, J.D. et al. Biotechnol. Bioeng. 99, 686–699 (2008).

    Article  CAS  PubMed  Google Scholar 

  4. Maier, K., Hofmann, U., Reuss, M. & Mauch, K. Biotechnol. Bioeng. 100, 355–370 (2008).

    Article  CAS  PubMed  Google Scholar 

  5. Nöh, K. et al. J. Biotechnol. 129, 249–267 (2007).

    Article  PubMed  Google Scholar 

  6. Yuan, J. et al. Nat. Chem. Biol. 2, 529–530 (2006).

    Article  CAS  PubMed  Google Scholar 

  7. Megason, S.G. & Fraser, S.E. Cell 130, 784–795 (2007).

    Article  CAS  PubMed  Google Scholar 

  8. Danuser, G. & Waterman-Storer, C.M. Annu. Rev. Biophys. Biomol. Struct. 35, 361–387 (2006).

    Article  CAS  PubMed  Google Scholar 

  9. Damm, E.M. & Pelkmans, L. Cell. Microbiol. 8, 1219–1227 (2006).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Hellerstein, M.K. Annu. Rev. Nutr. 23, 379–402 (2003).

    Article  CAS  PubMed  Google Scholar 

  11. Munger, J. et al. PLoS Pathog. 2, e132 (2006).

    Article  PubMed  PubMed Central  Google Scholar 

  12. Hellerstein, M.K. J. Pharmacol. Exp. Ther. 325, 1–9 (2008).

    Article  CAS  PubMed  Google Scholar 

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Sauer, U., Zamboni, N. From biomarkers to integrated network responses. Nat Biotechnol 26, 1090–1092 (2008). https://doi.org/10.1038/nbt1008-1090

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