A new method for solving X-ray crystal structures relies on the introduction of iodine into proteins in the form of p-iodophenylalanine.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Xie, J., Wang, L., Brock, A., Spraggon, G. & Schultz, P.G. Nat. Biotechnol. 22, XX–XX (2004).
Blundell, T.L. & Johnson, L.N. Protein Crystallography (Academic Press, New York, 1976).
Hendrickson, W.A. J. Synchrotron Rad. 6, 845–851 (1997).
Sigler, P.B. Biochemistry 9, 3609–3617 (1970).
Brzozowski, A.M. et al. Nature 351, 491–494 (1991).
Dauter, Z., Dauter, M. & Rajashankar, K.R. Acta Crystallogr. D56, 232–237 (2000).
Wang, L., Brock, A., Herberich, B. & Schultz, P.G. Science 292, 498–500 (2001).
Chin, J.W. et al. Science 301, 964–967 (2003).
Ravelli, R.B.G. & McSweeney, S.M. Structure 8, 315–328 (2000).
Zwart, P.H., Banumathi, S., Dauter, M. & Dauter, Z. Acta Crystallogr., in press (2004).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Dauter, Z. Phasing in iodine for structure determination. Nat Biotechnol 22, 1239–1240 (2004). https://doi.org/10.1038/nbt1004-1239
Issue Date:
DOI: https://doi.org/10.1038/nbt1004-1239
This article is cited by
-
Salvaging Pyrococcus furiosus Protein Targets at SECSG
Journal of Structural and Functional Genomics (2005)