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Knockout drug screens

Cell lines that differ by a single genetic change show promise in drug screens to identify compounds with gene-selective properties.

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Figure 1: Co-culture drug screening with isogenic “knockout” cells.

© Bob Crimi

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Prendergast, G. Knockout drug screens. Nat Biotechnol 19, 919–920 (2001). https://doi.org/10.1038/nbt1001-919

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  • DOI: https://doi.org/10.1038/nbt1001-919

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