Abstract
Antibiotic TA adheres avidly to a variety of surfaces. When administered orally or intravenously to animals, the antibiotic concentrates in an active form close to the site of administration. No measurable blood level of the antibiotic is found. Tissues treated with antibiotic TA and then washed continuously to remove unbound antibiotic retain bactericidal activity. Antibiotic TA may have applications in circumstances where an active bound antibiotic is desired.
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Rosenberg, E., Porter, J., Nathan, P. et al. Antibiotic TA: An Adherent Antibiotic. Nat Biotechnol 2, 796–799 (1984). https://doi.org/10.1038/nbt0984-796
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DOI: https://doi.org/10.1038/nbt0984-796
