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Clinical Systems for the Production of Human Cells and Tissues

Abstract

Ex vivo cell production systems are on the verge of changing clinical practice

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References

  1. Koller, M.R., Emerson, S.G., and Palsson, B.Ø. 1993. Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures. Blood 82(2): 378–84.

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  2. The Aastrom Cell Production System (Aastrom CPS) is in its prototype stage, and not yet approved or available for sale. Although initially targeted for use with bone-marrow-derived stem-cell mixtures, the Aastrom CPS has also been demonstrated to efficiently produce cells of different lineages and from different sources.

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Armstrong, R., Ogier, W. & Maluta, J. Clinical Systems for the Production of Human Cells and Tissues. Nat Biotechnol 13, 449–453 (1995). https://doi.org/10.1038/nbt0595-449

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  • DOI: https://doi.org/10.1038/nbt0595-449

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