Haploidy with histones

An engineered centromere-specific histone could enable homozygous diploid lines to be generated at high frequency, simplifying crop breeding.

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Figure 1: Manipulation of CENH3 structure perturbs chromosome segregation in plants.

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Author information

Correspondence to Daphne Preuss.

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Competing interests

D.L.P. is a founder and employee of Chromatin Inc., a company working on chromosome inheritance for the agricultural biotechnology industry.

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Copenhaver, G., Preuss, D. Haploidy with histones. Nat Biotechnol 28, 423–424 (2010). https://doi.org/10.1038/nbt0510-423

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