This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Lerner, R.A. 1982. Tapping the immunological repertoire to produce antibodies of predetermined specificity. Nature 299:592–596.
Panicali, D. and Paoletti, E. 1982. Construction of poxviruses as cloning vectors: Insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus. Proc. Natl. Acad. Sci. USA 79:4927–4931.
Smith, G.L., Mackett, M. and Moss, B. 1983. Infectious vaccinia virus recombinants that express hepatitis B virus surface antigen. Nature 302:490–495.
McAleer, W.J., Buynak, E.B., Maigetter, R.Z., Wambler, D.E., Miller, W.J. and Hilleman, M.R. 1984. Human hepatitis B vaccine from recombinant yeast. Nature 307:178–180.
Neurath, A.R., Kent, S.B., Parker, K., Prince, A.M., Strick, N., Brotman, B. and Sproul, P. 1986. Antibodies to a synthetic peptide from the preS 120–145 region of the hepatitis B virus envelope are virus-neutralizing. Vaccine 4:35–37.
Szmuness, W., Stevens, C.E. and Harley, E.J. 1980. Hepatitis B vaccine: Demonstration of efficacy in a controlled clinical trial in a high-risk population in the United States. N. Engl. J. Med. 303:833–841.
Seeff, L.B. 1984. Viral Hepatitis and Liver Diseases. Vyas, G. N., Dienstag, J. L. and Hoofnagle, J. H. (Eds.). Grune and Stratton, Florida.
Szmuness, W., Stevens, C.E., Oleszko, W.R. and Goodman, A. 1981. Passive-active immunization against hepatitis B: Immunogenicity studies in adult Americans. Lancet 1:575–577.
Ichimori, Y., Sasano, K., Ito, H., Hitotsumachi, S., Kimura, Y., Kaneko, K., Kida, M. and Tsukamoto, K. 1985. Establishment of hybridomas secreting human monoclonal antibodies against tetanus toxin and hepatitis B virus surface antigen. Biochem. Biophys. Res. Commun. 129:26–33.
Ichimori, Y., Harada, K., Hitotsumachi, S. and Tsukamoto, K. 1987. Establishment of hybridoma secreting human monoclonal antibody against hepatitis B surface antigen. Biochem. Biophys. Res. Commun. 142:805–812.
Prince, A.M., Szmuness, W. and Woods, K.R. 1971. Antibody against serum-hepatitis antigen: Prevalence and potential use as immune serum globulin in prevention of serum-hepatitis infections. N. Engl. J. Med. 285:933.
Kitano, K., Shintani, Y., Ichimori, Y., Tsukamoto, K., Sasai, S. and Kida, M. 1986. Production of human monoclonal antibodies by heterohybridomas. Appl. Microbiol. Biotechnol. 24:282–286.
Ito, Y., Hayakawa, T. and Fujisawa, Y. 1986. Expression of hepatitis B virus surface antigen P31 gene in yeast. Biochem. Biophys. Res. Commun. 138:268–274.
Ito, Y. and Fujisawa, Y. 1986. Synthesis in yeast of hepatitis B virus surface antigen modified P31 particles by gene modification. Biochem. Biophys. Res. Commun. 141:942–948.
Kitano, K., Nakao, M., Ito, Y. and Fujisawa, Y. 1987. Recombinant hepatitis B virus surface antigen P31 accumulates as particles in Saccharomyces cerevisiae. Bio/Technology 5:281–283.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Harada, K., Ichimori, Y., Sasano, K. et al. Human–Human Hybridomas Secreting Hepatitis B Virus–Neutralizing Antibodies. Nat Biotechnol 7, 374–377 (1989). https://doi.org/10.1038/nbt0489-374
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/nbt0489-374