Only a subset of genetic variants can be examined in genome-wide surveys for genetic risk factors. How can a fixed set of markers account for the entire genome by acting as proxies for neighboring associations?
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Acknowledgements
E.H. is a faculty fellow of the Edmond J. Safra Bioinformatics program at Tel Aviv Univerity.
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Halperin, E., Stephan, D. Maximizing power in association studies. Nat Biotechnol 27, 255–256 (2009). https://doi.org/10.1038/nbt0309-255
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DOI: https://doi.org/10.1038/nbt0309-255
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