On 5 January, the American Association for Cancer Research (AACR) made the first public release of 19,000 de-identified genomic records obtained through its project GENIE (Genomics Evidence Neoplasia Information Exchange). The data set contains genomic data collected from cancer patients treated at eight institutions in the US, Canada, the Netherlands and France. It is among the largest fully public cancer genomic data sets released to date, the AACR said in a press release. The findings were generated from patients whose tumors were sequenced as part of their routine care. The information was then pooled into a single registry and linked to selected longitudinal outcomes. The registry encompasses patients with 59 major cancer types, including nearly 3,000 with lung cancer and more than 2,000 with colorectal cancer. GENIE was launched in November 2015. Its goal is to provide a database for scientists to generate research hypotheses spanning translational to clinical studies, including those that would inform new or ongoing clinical trials; validate biomarkers; reposition or repurpose drugs; add new mutations to existing drug labels; and identify new targets. Because it will be enriched with examples of late-stage disease, the data from GENIE could also provide payers with the evidence base necessary to support reimbursement for next-generation sequence-based testing. This initial data set is available from the AACR website or by download from informatics partner Sage Bionetworks. The consortium is now accepting applications for new participating centers to expand the registry, a year ahead of schedule.