Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

Meehan, T.F. et al. Nat. Genet. 10.1038/ng.3901 (2017)

Pilot study of large-scale production of mutant pigs by ENU mutagenesis

Hai, T. et al. eLife 6, e26248 (2017)

Quantifiable predictive features define epitope-specific T cell receptor repertoires

Dash, P. et al. Nature 547, 89–93 (2017)

Identifying specificity groups in the T cell receptor repertoire

Glanville, J. et al. Nature 547, 94–98 (2017)

Massively parallel biophysical analysis of CRISPR-Cas complexes on next generation sequencing chips

Jung, C. et al. Cell 170, 35–47.e13 (2017)

The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial

Rouphael, N.G. et al. Lancet 10.1016/S0140-6736(17)30575-5 (2017)