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Genome editing for clinical HIV isolates

An engineered recombinase removes the HIV-1 provirus from patient-derived cells and reduces infection in humanized mice.

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Figure 1: Summary of the current HIV-1 cure strategies and their primary obstacles.

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Correspondence to Robert F Siliciano.

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Kim, M., Siliciano, R. Genome editing for clinical HIV isolates. Nat Biotechnol 34, 388–389 (2016). https://doi.org/10.1038/nbt.3531

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