Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Tumour exosome integrins determine organotropic metastasis

Hoshino, A. et al. Nature doi:10.1038/nature15756 (28 October 2015)

Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

Lehar, S.M. et al. Nature doi:10.1038/nature16057 (4 November 2015)

Genome-wide inactivation of porcine endogenous retroviruses (PERVs)

Yang, L. et al. Science doi:10.1126/science.aad1191 (11 October 2015)

Library preparation methodology can influence genomic and functional predictions in human microbiome research

Jones, M.B. et al. PNAS doi:10.1073/pnas.1519288112 (29 September 2015)

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

Gao, H. et al. Nat. Med. doi:10.1038/nm.3954 (19 October 2015)