News & Views | Published:

A BiTE from cancer's intracellular menu

Nature Biotechnology volume 33, pages 10401041 (2015) | Download Citation

T cells are targeted to tumor cells expressing an intracellular antigen using a bispecific antibody.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    et al. Nat. Biotechnol. 33, 1079–1086 (2015).

  2. 2.

    et al. Proc. Natl. Acad. Sci. USA 99, 9421–9426 (2002).

  3. 3.

    et al. Sci. Transl. Med. 5, 176ra133 (2013).

  4. 4.

    et al. Clin. Cancer Res. 15, 5323–5337 (2009).

  5. 5.

    et al. Clin. Cancer Res. 20, 4036–4046 (2014).

  6. 6.

    , , , & Mol. Immunol. 43, 763–771 (2006).

  7. 7.

    et al. Sci. Transl. Med. 5, 174ra127 (2013).

  8. 8.

    & Science 348, 69–74 (2015).

  9. 9.

    et al. Sci. Transl. Med. 5, 197ra103 (2013).

  10. 10.

    et al. J. Clin. Oncol. 32, 4134–4140 (2014).

Download references

Author information

Affiliations

  1. Alexander I. Salter and Stanley R. Riddell are at the Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

    • Alexander I Salter
    •  & Stanley R Riddell
  2. The University of Washington School of Medicine, Seattle, Washington, USA.

    • Alexander I Salter
    •  & Stanley R Riddell

Authors

  1. Search for Alexander I Salter in:

  2. Search for Stanley R Riddell in:

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Stanley R Riddell.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nbt.3370

Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing