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Sex-ratio-biasing constructs for the control of invasive lower vertebrates

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Figure 1: Effects of the FL constructs on sex ratios and reproductive parameters in zebrafish and common carp.
Figure 2: Potential synergy between the release of a sex-biasing gene construct and classic biological control.


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We thank J. Barrett, D. Bornholdt, W.L. Chadderton, R. Devlin, P. Eimon, K. Hayes, A. Kapuskinski, P. Koopman, K. McColl, L. McFarlane, R. Mcloughlin, S. Robert, P. Sorensen, J. Teem and the participants in the First International Symposium on Genetic Biocontrol of Fish for helpful comments on different aspects of the work; R. Gurney and X. Mu for assistance in the laboratory; L. Alphey and F. Gould for comments on the manuscript; and the Murray-Darling Basin Authority for their financial support for the project.

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Correspondence to Ronald Thresher.

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Supplementary Figures 1–13, Supplementary Methods and Supplementary Results (PDF 1128 kb)

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Thresher, R., van de Kamp, J., Campbell, G. et al. Sex-ratio-biasing constructs for the control of invasive lower vertebrates. Nat Biotechnol 32, 424–427 (2014).

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