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Next-generation sequencing in the clinic

Nature Biotechnology volume 31, pages 990992 (2013) | Download Citation

Pools of cell lines carrying a variety of known mutations are used to validate the performance of a cancer diagnostic test based on next-generation sequencing.

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Author information


  1. Jason Y. Park is at the Department of Pathology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, Texas, USA, and the Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

    • Jason Y Park
  2. Larry J. Kricka is at the Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA.

    • Larry J Kricka
  3. Paolo Fortina is at the Cancer Genomics Laboratory, Kimmel Cancer Center, Department of Cancer Biology, Thomas Jefferson University, Jefferson Medical College, Philadelphia, Pennsylvania, USA.

    • Paolo Fortina


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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Jason Y Park.

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