Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Cardiac regenerative medicine 2.0

The key challenge in the field of molecular and cell-based therapies for heart regeneration is controlled delivery.

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Effects of current molecular therapies when administered in the infarct regions of the murine heart.

Katie Vicari

References

  1. Ptaszek, L.M., Mansour, M., Ruskin, J.N. & Chien, K.R. Lancet 379, 933–942 (2012).

    Article  Google Scholar 

  2. Eulalio, A. et al. Nature 492, 376–381 (2012).

    Article  CAS  Google Scholar 

  3. Jayawardena, T.M. et al. Circ. Res. 110, 1465–1473 (2012).

    Article  CAS  Google Scholar 

  4. Yoo, A.S. et al. Nature 476, 228–231 (2011).

    Article  CAS  Google Scholar 

  5. Hausenloy, D.J. & Yellon, D.M. Cardiovasc. Res. 83, 179–194 (2009).

    Article  CAS  Google Scholar 

  6. Nagai, T. & Komuro, I. Am. J. Physiol. Heart Circ. Physiol. 303, H501–H512 (2012).

    Article  CAS  Google Scholar 

  7. Bock-Marquette, I., Saxena, A., White, M.D., Dimaio, J.M. & Srivastava, D. Nature 432, 466–472 (2004).

    Article  CAS  Google Scholar 

  8. Huang, G.N. et al. Science 338, 1599–1603 (2012).

    Article  CAS  Google Scholar 

  9. Song, K. et al. Nature 485, 599–604 (2012).

    Article  CAS  Google Scholar 

  10. Qian, L. et al. Nature 485, 593–598 (2012).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kenneth R Chien.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Soh, BS., Wu, H. & Chien, K. Cardiac regenerative medicine 2.0. Nat Biotechnol 31, 209–211 (2013). https://doi.org/10.1038/nbt.2524

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt.2524

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing