An additional layer of RNA regulation in which RNAs encoded by genes and pseudogenes compete for microRNAs could offer new opportunities for oligonucleotide therapeutics.
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A.K. is employed by RXi Pharmaceuticals, Worcester, Massachusetts, USA.
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Khvorova, A., Wolfson, A. New competition in RNA regulation. Nat Biotechnol 30, 58–59 (2012). https://doi.org/10.1038/nbt.2092
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DOI: https://doi.org/10.1038/nbt.2092