Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Physiology

Mechanosensor of lung inflation identified

Nature volume 541, pages 165–166 (2017)Cite this article

Subjects

The Piezo2 protein senses changes in lung volume, acting in different neurons to convey this information to the brain. This finding adds to the list of roles for Piezo2 in mechanosensation. See Article p.176

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Regulation of respiration by Piezo2.

Notes

  1. See all news & views

References

  1. Nonomura, K. et al. Nature 541, 176–181 (2017).

    Article  ADS  CAS  Google Scholar 

  2. Hering, E. & Breuer, J. Sitzungsber. Akad. Wiss. Wien 57, 672–677 (1868).

    Google Scholar 

  3. Lee, L. Y. & Yu, J. Comp. Physiol. 4, 287–324 (2014).

    Article  Google Scholar 

  4. Chang, R. B., Strochlic, D. E., Williams, E. K., Umans, B. D. & Liberles, S. D. Cell 161, 622–633 (2015).

    Article  CAS  Google Scholar 

  5. Ranade, S. S., Syeda, R. & Patapoutian, A. Neuron 87, 1162–1179 (2015).

    Article  CAS  Google Scholar 

  6. Tryfon, S., Kontakiotis, T., Mavrofridis, E. & Patakas, D. Respiration 68, 140–144 (2001).

    Article  CAS  Google Scholar 

  7. Schelegle, E. S. & Green, J. F. Respir. Physiol. 125, 17–31 (2001).

    Article  CAS  Google Scholar 

  8. Hasan, S. U., Lalani, S. & Remmers, J. E. Respir. Physiol. 119, 133–141 (2000).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Christo Goridis is at the Institut de Biologie de l'Ecole normale supérieure (IBENS), INSERM, CNRS, PSL Research University, 75005 Paris, France.,

    Christo Goridis

Authors
  1. Christo Goridis
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Christo Goridis.

Related links

Related links

Related links in Nature Research

Cell biology: The sensation of stretch

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Goridis, C. Mechanosensor of lung inflation identified. Nature 541, 165–166 (2017). https://doi.org/10.1038/nature21111

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature21111

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing