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Metastasis

Pathways of parallel progression

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Two studies in mice identify mechanisms by which tumour cells disseminate in very early breast cancer. Both show that these cells colonize distant tissues more efficiently than their later counterparts. See Article p.552 & Letter p.588

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Figure 1: Mechanisms of early dissemination and metastasis in breast cancer.

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Correspondence to Cyrus M. Ghajar or Mina J. Bissell.

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Ghajar, C., Bissell, M. Pathways of parallel progression. Nature 540, 528–529 (2016). https://doi.org/10.1038/nature21104

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