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In retrospect

Eighty years of stress

The discovery in 1936 that rats respond to various damaging stimuli with a general response that involves alarm, resistance and exhaustion launched the discipline of stress research.

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Figure 1: Hans Selye outlines the general adaptation syndrome.

Don Graham/Division de la Gestion de Documents et des Archives, Univ. Montréal


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Correspondence to George Fink.

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Fink, G. Eighty years of stress. Nature 539, 175–176 (2016).

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