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Neuroscience

In search of the memory molecule

Nature volume 535, pages 4142 (07 July 2016) | Download Citation

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The protein PKM-ζ has been proposed to regulate the maintenance of memory in rodents, but this theory has been questioned. The finding that another isoform of the protein acts as a backup if PKM-ζ is lacking will influence this debate.

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Author information

Affiliations

  1. Paul W. Frankland and Sheena A. Josselyn are in the Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada. They are also in the Departments of Physiology and Psychology and at the Institute of Medical Science, University of Toronto, Toronto.

    • Paul W. Frankland
    •  & Sheena A. Josselyn

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DOI

https://doi.org/10.1038/nature18903

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