The mechanisms that underlie enforced transitions between mature cell lineages are poorly understood. Profiling single skin cells that are induced to become neurons reveals that, unexpectedly, they often become muscle. See Letter p.391
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Di Stefano, B., Hochedlinger, K. Brain versus brawn. Nature 534, 332–333 (2016). https://doi.org/10.1038/nature18444
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DOI: https://doi.org/10.1038/nature18444