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Microbiology

Pumping persisters

Nature volume 534, pages 4142 (02 June 2016) | Download Citation

The finding that antibiotics are pumped out of drug-tolerant bacterial cells by the TolC protein complex provides insight into how some cells, known as persisters, survive in the face of antibiotic treatments.

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References

  1. 1.

    Lancet ii, 497–500 (1944).

  2. 2.

    , , , & Science 305, 1622–1625 (2004).

  3. 3.

    , & Cell 154, 1140–1150 (2013).

  4. 4.

    , & Annu. Rev. Microbiol. 62, 193–210 (2008).

  5. 5.

    et al. Mol. Cell 62, 284–294 (2016).

  6. 6.

    , , & Proc. Natl Acad. Sci. USA 108, 13206–13211 (2011).

  7. 7.

    et al. Science 343, 204–208 (2014).

  8. 8.

    et al. Mol. Cell. 59, 9–21 (2015).

Download references

Author information

Affiliations

  1. Kenn Gerdes and Szabolcs Semsey are in the Department of Biology, University of Copenhagen, DK-2200 Copenhagen, Denmark.

    • Kenn Gerdes
    •  & Szabolcs Semsey

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Correspondence to Kenn Gerdes.

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DOI

https://doi.org/10.1038/nature18442

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