Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Biological techniques

Kidney tissue grown from induced stem cells

Engineered human cells that can give rise to every cell type have been induced to generate structures that resemble an embryonic kidney. This advance charts a course towards growing transplantable kidneys in culture. See Letter p.564

This is a preview of subscription content

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: From stem cell to self-organizing tissue.


  1. 1.

    See all news & views


  1. 1

    Takasato, M. et al. Nature 526, 564–568 (2015).

    ADS  CAS  Article  Google Scholar 

  2. 2

    Carrel, A. & Burrows, M. J. Am. Med. Assoc. 55, 2057–2058 (1910).

    Article  Google Scholar 

  3. 3

    Unbekandt, M. & Davies, J. A. Kidney Int. 77, 407–416 (2010).

    Article  Google Scholar 

  4. 4

    Lusis, M., Li, J., Ineson, J., Christensen, M. E., Rice, A. & Little, M. H. Stem Cell Res. 5, 23–39 (2010).

    CAS  Article  Google Scholar 

  5. 5

    Lawrence, M. L., Chang, C. H. & Davies, J. A. Sci. Rep. 13, 9092 (2015).

    Article  Google Scholar 

  6. 6

    Rogers, S. A., Lowell, J. A., Hammerman, N. A. & Hammerman, M. R. Kidney Int. 54, 27–37 (1998).

    CAS  Article  Google Scholar 

  7. 7

    Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).

    CAS  Article  Google Scholar 

  8. 8

    Kim, D. & Dressler, G. R. J. Am. Soc. Nephrol. 16, 3527–3534 (2005).

    CAS  Article  Google Scholar 

  9. 9

    Fletcher, A. P. J. R. Soc. Med. 71, 693–696 (1978).

    CAS  Article  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to Jamie A. Davies.

Related links

Related links

Related links in Nature Research

Developmental neuroscience: Miniature human brains

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Davies, J. Kidney tissue grown from induced stem cells. Nature 526, 512–513 (2015).

Download citation


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing