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Opening LOX to metastasis


New findings implicate the enzyme lysyl oxidase (LOX), secreted by oxygen-deprived breast cancer cells, in inducing bone lesions that precede and facilitate the spread of the cancer cells to the bone. See Letter p.106

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Figure 1: Pre-metastatic niche formation in bone.


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Correspondence to Neta Erez.

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Erez, N. Opening LOX to metastasis. Nature 522, 41–42 (2015).

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