Blood stem cells derive at least in part from an embryonic vessel called the dorsal aorta. It emerges that a flanking tissue called the somite contributes cells and signals to this process. See Letters p.314 & p.319
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Sawamiphak, S., Stainier, D. It takes muscle to make blood cells. Nature 512, 257–258 (2014). https://doi.org/10.1038/nature13740
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DOI: https://doi.org/10.1038/nature13740
