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Stem cells in multiple time zones

In fruitfly larvae, neural stem cells generate different cell types at different times. It emerges that these temporal progressions are controlled by multiple cascades of gene transcription factors. See Articles p.449 & p.456

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Figure 1: Time-dependent evolution of neural lineage trees.


  1. *This article and the papers under discussion7,8 were published online on 19 June 2013.


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Correspondence to Stefan Thor.

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Thor, S. Stem cells in multiple time zones. Nature 498, 441–443 (2013).

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