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Neuroscience

Memory and the single molecule

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Sustained activity of the brain-specific enzyme PKM-ζ is thought to underlie the maintenance of long-term memories. Studies in PKM-ζ-deficient mice, however, cast the importance of this protein into question. See Letters p.416 & p.420

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  1. *This article and the paper under discussion1,2 were published online on 2 January 2013.

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Correspondence to Paul W. Frankland.

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Frankland, P., Josselyn, S. Memory and the single molecule. Nature 493, 312–313 (2013). https://doi.org/10.1038/nature11850

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