Lindahl, T., Satoh, M. S., Poirier, G. G. & Klungland, A.
Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks. Trends Biochem. Sci.
20, 405–411 (1995)
D'Amours, D., Desnoyers, S., D'Silva, I. & Poirier, G. G.
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J.
342, 249–268 (1999)
El-Khamisy, S. F., Masutani, M., Suzuki, H. & Caldecott, K. W.
A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage. Nucleic Acids Res.
31, 5526–5533 (2003)
Loss of poly(ADP-ribose) polymerase-1 causes increased tumour latency in p53-deficient mice. EMBO J.
20, 3535–3543 (2001)
de Murcia, J. M.
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc. Natl Acad. Sci. USA
94, 7303–7307 (1997)
Wang, Z. Q.
PARP is important for genomic stability but dispensable in apoptosis. Genes Dev.
11, 2347–2358 (1997)
Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells. EMBO J.
12, 2109–2117 (1993)
Schultz, N., Lopez, E., Saleh-Gohari, N. & Helleday, T.
Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination. Nucleic Acids Res.
31, 4959–4964 (2003)
Yang, Y. G., Cortes, U., Patnaik, S., Jasin, M. & Wang, Z. Q.
Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks. Oncogene
23, 3872–3882 (2004)
Griffin, C. S., Simpson, P. J., Wilson, C. R. & Thacker, J.
Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation. Nature Cell Biol.
2, 757–761 (2000)
Tebbs, R. S.
Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene. Proc. Natl Acad. Sci. USA
92, 6354–6358 (1995)
Bowman, K. J., Newell, D. R., Calvert, A. H. & Curtin, N. J.
Differential effects of the poly(ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro
. Br. J. Cancer
84, 106–112 (2001)
Skalitzky, D. J.
Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors. J. Med. Chem.
46, 210–213 (2003)
Kraakman-van der Zwet, M.
Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions. Mol. Cell. Biol.
22, 669–679 (2002)
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature doi:10.1038/nature03445 (this issue)
Venkitaraman, A. R.
Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell
108, 171–182 (2002)
Menissier de Murcia, J.
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse. EMBO J.
22, 2255–2263 (2003)
Instability and decay of the primary structure of DNA. Nature
362, 709–715 (1993)
Paull, T. T.
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol.
10, 886–895 (2000)
Arnaudeau, C., Lundin, C. & Helleday, T.
DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells. J. Mol. Biol.
307, 1235–1245 (2001)
Caldecott, K. W., Tucker, J. D. & Thompson, L. H.
Construction of human XRCC1 minigenes that fully correct the CHO DNA repair mutant EM9. Nucleic Acids Res.
20, 4575–4579 (1992)
Calabrese, C. R.
Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361. J. Natl Cancer Inst.
96, 56–67 (2004)
Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines. Hum. Mol. Genet.
11, 2189–2200 (2002)
Halldorsson, H., Gray, D. A. & Shall, S.
Poly (ADP-ribose) polymerase activity in nucleotide permeable cells. FEBS Lett.
85, 349–352 (1978)
Grube, K., Kupper, J. H. & Burkle, A.
Direct stimulation of poly(ADP ribose) polymerase in permeabilized cells by double-stranded DNA oligomers. Anal. Biochem.
193, 236–239 (1991)
RAD51 is involved in repair of damage associated with DNA replication in mammalian cells. J. Mol. Biol.
328, 521–535 (2003)