Ex vivo patch clamp electrophysiology (holding voltage: −70 mV) of endogenous pyramidal neurons demonstrated significantly higher sIPSC amplitudes and shorter inter-event intervals compared to dead cell controls. When TTX was added and mIPSCs were analyzed, the difference in amplitudes between groups was eliminated, but inter-event intervals remained shorter compared to dead cell controls. Example traces are depicted and a representative pyramidal cell, labeled with neurobiotin, is shown. Scale bar is 50 μm. n=13–34 cells from 2–3 rats/group. For more information on this topic, please refer to the article by Donegan et al. on pages 1492–1501.