Abstract
The RSPCA/UFAW Rodent Welfare Group holds a one-day meeting every autumn for its members to discuss current welfare research and exchange views on rodent welfare issues. A key aim of the group is to encourage people to think about the whole lifetime experience of laboratory rodents, ensuring that every potential impact on their well-being has been reviewed and refined. The 2005 meeting focused on the refinement of techniques used in the creation of GM rodents, especially genotyping and vasectomy.
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References
Dantzer, R. et al. Mechanisms of the behavioural effects of cytokines. Adv. Exp. Med. Biol. 461, 83–105 (1999).
Dantzer, R. et al. Molecular basis of sickness behavior. Ann. N.Y. Acad. Sci. 856, 132–138 (1998).
Felton, L.M. et al. MCP-1 and murine prion disease: Separation of early behavioural dysfunction from overt clinical disease. Neurobiol. Dis. 20(2), 283–295 (2005).
Dudek, B.C., Adams, N., Boice, R. & Abbott, M.E. Genetic influences on digging behaviors in mice (Mus musculus) in laboratory and seminatural settings. J. Comp. Psychol. 97(3), 249–259 (1983).
Cunningham, C. et al. Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease. Eur. J. Neurosci. 17(10), 2147–2155 (2003).
Cunningham, C. et al. Neuropathologically distinct prion strains give rise to similar temporal profiles of behavioral deficits. Neurobiol. Dis. 18(2), 258–269 (2005).
Xu, X.J. et al. Systemic mexiletine relieves chronic allodynialike symptoms in rats with ischemic spinal cord injury. Anesth. Analg. 74(5), 649–652 (1992).
Lu, Y. & Westlund, K.N. Gabapentin attenuates nociceptive behaviors in an acute arthritis model in rats. J. Pharmacol. Exp. Ther. 290(1), 214–219 (1999).
Narsinghani, U. & Anand, K.J. Developmental neurobiology of pain in neonatal rats. Lab Anim. (NY) 29(9), 27–39 (2000).
VAAWF/FRAMA/RSPCA/UFAW Joint Working Group on Refinement. Refinement and reduction in production of genetically modified mice. Lab. Anim. 37(Suppl 1), 1–49 (2003)
Council of Europe. Council Directive of 24 November 1986 on the Approximation of Laws, Regulations and Administrative Provisions of the Member States regarding the Protection of Animals used for Experimental and Other Scientific Purposes (Official Journal of the European Communities L358, Luxembourg, 1986).
Acknowledgements
The Group thanks the speakers and everyone who attended and participated in the meeting. Thanks also to Joanne Wright for her administrative skills.
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Hawkins, P., Felton, L., van Loo, P. et al. Report of the 2005 RSPCA/UFAW Rodent Welfare Group meeting. Lab Anim 35, 29–38 (2006). https://doi.org/10.1038/laban1006-29
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DOI: https://doi.org/10.1038/laban1006-29