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Best practices for cardiac magnetic resonance imaging in common large animal research models


Magnetic resonance imaging has proven to be useful for the study of cardiovascular physiology in health and disease; it provides important data and information about healthy and diseased states in humans and animals, and it facilitates the safe characterization and positioning of medical devices during cardiovascular applications. Looking to the future, magnetic resonance imaging will continue to play a formative role in biomedical research and applications. Here, we discuss how to avoid common pitfalls and provide safe transport, anesthetic support and physiologic support for animals that are used in dedicated or shared cardiovascular imaging facilities.

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  1. 1

    Taylor, J. & Hampshire, V. Basic research support for shared magnetic resonance imaging resources. Lab Anim. (NY) 44, 435–437 (2015).

    Article  Google Scholar 

  2. 2

    French, B.A. Animal models in cardiovascular MRI research: value and limitations. Curr. Cardiovasc. Imaging Rep. 5, 99–108 (2012).

    Article  Google Scholar 

  3. 3

    Vallee, J.P., Ivancevic, M.K., Nguyen, D., Morel, D.R. & Jaconi, M. Current status of cardiac MRI in small animals. MAGMA. 17, 149–156 (2004).

    Article  Google Scholar 

  4. 4

    Lukasik, V.M. & Gillies, R.J. Animal anaesthesia for in vivo magnetic resonance. NMR Biomed. 16, 459–467 (2003).

    CAS  Article  Google Scholar 

  5. 5

    Niendorf, T., Winter, L. & Frauenrath, T. Electrocardiogram in an MRI environment: clinical needs, practical considerations, safety implications, technical solutions and future directions. in Advances in Electrocardiograms—Methods and Analysis. (ed. Millis, R.M.) 309–325 (InTech, Rijeka, Croatia, 2012).

    Google Scholar 

  6. 6

    Saremi, F., Grizard, J.D. & Kim, R.J. Optimizing cardiac MR imaging: practical remedies for artifacts. Radiographics 28, 1161–1187 (2008).

    Article  Google Scholar 

  7. 7

    Lisanti, C.J. & Douglas, D.B. Effects of breath-hold and cardiac cycle on the MRI appearance of the aorta and inferior vena cava in T2 abdominal imaging. AJR Am. J. Roentgenol. 192, 1348–1358 (2009).

    Article  Google Scholar 

  8. 8

    Hampshire, V. CRISPR/Cas9 and the future of clinical research. Lab Anim. (NY) 45, 89–90 (2016).

    Article  Google Scholar 

Download references


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Taylor, J., Hampshire, V. Best practices for cardiac magnetic resonance imaging in common large animal research models. Lab Anim 45, 169–171 (2016).

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