Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Clinical Techniques
  • Published:

Altered states part 1: ancillary refinements in managing perioperative distress with canines

Abstract

The biomedical research community has made great progress over the last 30 years in improving strategies to detect and manage pain. Managing experimental and procedural anxiety is a more challenging task, and it depends on the continued practice of distinguishing normal and abnormal states of physiology and behavior in animal subjects1. Common approaches for managing pain and distress can be optimized by implementing a plan to also monitor and manage anxiety and dysphoria.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Karas, A. Pain, anxiety, or dysphoria - how to tell? A video assessment lab. in Proc. Am. Coll. Vet. Surg. Vet. Symp. (Chicago, IL, 2011).

    Google Scholar 

  2. US Department of Agriculture. Animals Used in Research 2014. https://www.aphis.usda.gov/animal_welfare/downloads/7023/Animals%20Used%20In%20Research%202014.pdf.

  3. Call, J. Brauer, J. Kaminski, J. & Tomasello, M. Domestic dogs (Canis familiaris) are sensitive to the attentional state of humans. J. Comp. Psychol. 3, 257–263 (1981).

    Google Scholar 

  4. Becker, W.M., Mama, K.R., Rao, R.S., Palmer, R.H. & Egger, E.L. Prevalence of dysphoria after fentanyl in dogs undergoing stifle surgery. Vet. Surg., 42, 302–307 (2013).

    Article  Google Scholar 

  5. Hellyer, P.W. & Falls, A.D. Pain management for the surgical patient. in Textbook of Small Animal Surgery vol. 1, 3rd edn. (ed. Slatter, D.H.) 2503–2515 (W.B. Saunders, Philadelphia, PA, 2003).

    Google Scholar 

  6. US Department of Agriculture. Animal Care Policy Manual (USDA, Riverdale, MD, 2015).

  7. Epstein, M.E. Transoperative pain management - how to be in the 95th percentile. in Proc. Western States Vet. Conf. (Las Vegas, Nevada, 2012).

    Google Scholar 

  8. US Food and Drug Administration. Orange Book: Approved Drug Products with Therapeutic Equivalence Evaluations (US Food and Drug Administration, Silver Spring, MD, 1997). http://www.accessdata.fda.gov/scripts/cder/ob/. Accessed 27 October 2015.

  9. Plumb, D.C. Plumb's Veterinary Drug Handbook 8th edn. (Wiley Blackwell, Ames, IA, 2015).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Victoria Hampshire.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hampshire, V. Altered states part 1: ancillary refinements in managing perioperative distress with canines. Lab Anim 45, 17–18 (2016). https://doi.org/10.1038/laban.907

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/laban.907

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing