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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Alveolar capillary dysplasia with misalignment of the pulmonary veins associated with aortic coarctation and intestinal malrotation

Journal of Perinatology volume 34, pages 795–797 (2014)Cite this article

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Abstract

Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) is a rare and lethal cause of refractory pulmonary hypertension of the newborn. We describe the clinical course of a neonate with refractory pulmonary hypertension diagnosed with ACD/MPV, aortic coarctation and other not previously reported associated malformations.

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References

  1. Janney CG, Askin FB, Kuhn C 3rd . Congenital alveolar capillary dysplasia: an unusual cause of repiratory distress in the newborn. Am J Clin Pathol 1981; 76: 722–727.

    Article  CAS  Google Scholar 

  2. Bishop NB, Stankiewitcz P, Steinhorn RH . Alveolar capillary dysplasia. Am J Respir Crit Care Med 2011; 184: 172–179.

    Article  Google Scholar 

  3. Michalsky MP, Arca MJ, Groenman F, Hammond S, Tibboel D, Caniano DA . Alveolar capillary dysplasia: a logical approach to a fatal disease. J Pediatr Surg 2005; 40: 1100–1105.

    Article  Google Scholar 

  4. Dishop MK . Paediatric interstitial lung disease: classification and definitions. Paediatr Respir Rev 2011; 12: 230–237.

    Article  Google Scholar 

  5. Drut R . Capillary apposition and density in the diagnosis of alveolar capillary dysplasia. Histopathology 2010; 56: 401–402.

    Article  Google Scholar 

  6. Melly L, Sebire NJ, Malone M, Nicholson AG . Capillary apposition and density in the diagnosis of alveolar capillary dysplasia. Histopathology 2008; 53: 450–457.

    Article  CAS  Google Scholar 

  7. Singh SA, Ibrahim T, Clark DJ, Taylor RS, George DH . Persistent pulmonary hypertension of newborn due to congenital capillary alveolar dysplasia. Pediatr Pulmonol 2005; 40: 349–353.

    Article  Google Scholar 

  8. Yachnis AT . Cerebellar heterotopia and dysplasia. In: Golden JA, Harding BN (eds). Pathology and Genetics. Developmental Neuropathology. ISN Neuropath Press: Basel, 2004; p 100.

    Google Scholar 

  9. Eulmesekian P, Cutz E, Parvez B, Bohn D, Adatia I . Alveolar capillary dysplasia: a six-year single center experience. J Perinat Med 2005; 33: 347–352.

    Article  Google Scholar 

  10. Inwald D, Brown K, Gensini F, Malone M, Goldman A . Open lung biopsy in neonatal and paediatric patients referred for extracorporeal membrane oxygenation (ECMO). Thorax 2004; 59: 328–333.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatric Cardiology, La Paz Children's Hospital, Madrid, Spain

    V Arreo del Val, L Deiros & M J Del Cerro

  2. Department of Neonatology, Neonatal Intensive Care Unit, La Paz Children's Hospital, Madrid, Spain

    A Avila-Alvarez

  3. Department of Anatomic Pathology, La Paz University Hospital, Madrid, Spain

    L R Schteffer

  4. Department of Genetics and Molecular Biology, La Paz University Hospital, Madrid, Spain

    F Santos

Authors
  1. V Arreo del Val
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  2. A Avila-Alvarez
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  3. L R Schteffer
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  4. F Santos
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  5. L Deiros
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  6. M J Del Cerro
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Corresponding author

Correspondence to V Arreo del Val.

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The authors declare no conflict of interest.

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Supplementary Information accompanies the paper on the Journal of Perinatology website

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Arreo del Val, V., Avila-Alvarez, A., Schteffer, L. et al. Alveolar capillary dysplasia with misalignment of the pulmonary veins associated with aortic coarctation and intestinal malrotation. J Perinatol 34, 795–797 (2014). https://doi.org/10.1038/jp.2014.94

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  • DOI: https://doi.org/10.1038/jp.2014.94

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