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Albumin versus saline: an open question

Journal of Perinatology volume 28, page 586 (2008)Cite this article

We have read with great interest the paper by Lynch et al.1 This study included 100 newborns with hypotension in the first 24 h of life, treated with either albumin or normal saline bolus and dopamine infusion when necessary. In the albumin group, the percentage of infants who achieved normal pressure 1 h after the first bolus, the degree of improvement and the duration of normal pressure were greater with lesser need for dopamine infusion. Surprisingly, the incidence of all intraventricular hemorrhage (IVH) in the normal saline group was significantly greater.

We wish to make some comments thereon.

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References

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Authors and Affiliations

  1. NICU, Institute of Pediatrics and Neonatology, Fondazione IRCCS ‘Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena,’ University of Milan, Milano, Italy

    S Ghirardello & F Mosca

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  1. S Ghirardello
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  2. F Mosca
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Correspondence to S Ghirardello.

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Ghirardello, S., Mosca, F. Albumin versus saline: an open question. J Perinatol 28, 586 (2008). https://doi.org/10.1038/jp.2008.77

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