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The ambulatory arterial stiffness index is not affected by night-time blood pressure characteristics

Journal of Human Hypertension volume 23, pages 680–682 (2009)Cite this article

Ambulatory arterial stiffness index (AASI), a measure derived from ambulatory blood pressure (BP) measurements, is a marker of arterial stiffness and a predictor of cardiovascular mortality. Yet, AASI has been contested due to its dependence on the degree of the nocturnal BP reduction in hypertensive patients. Excluding night-time BP readings, and thus the dipping information, we demonstrate that daytime AASI remains elevated in hypertensive children and adults and maintains the relationship with age, pulse pressure and systolic or diastolic BP.

The ambulatory arterial stiffness index (AASI), as derived from ambulatory blood pressure (BP) measurements, has been shown to correlate with classical measures of arterial stiffness, such as pulse wave velocity,1 and to provide similar prognostic information on cardiovascular mortality and target organ damage.2, 3, 4

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Author notes

  1. M G Mohaupt

    Present address: Division of Molecular and Vascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA

Authors and Affiliations

  1. Department of Pediatrics, Inselspital, Bern University Hospital, Berne, Switzerland

    M Vincenti, R O von Vigier & G D Simonetti

  2. Division of Pediatric Nephrology, University Children's Hospital Heidelberg, Heidelberg, Germany

    E Wühl & G D Simonetti

  3. Department of Nephrology and Hypertension, Inselspital, Bern University Hospital, Berne, Switzerland

    M G Mohaupt

Authors
  1. M Vincenti
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  2. R O von Vigier
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  3. E Wühl
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  4. M G Mohaupt
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  5. G D Simonetti
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Corresponding author

Correspondence to G D Simonetti.

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Vincenti, M., von Vigier, R., Wühl, E. et al. The ambulatory arterial stiffness index is not affected by night-time blood pressure characteristics. J Hum Hypertens 23, 680–682 (2009). https://doi.org/10.1038/jhh.2009.25

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