Abstract
A novel polymorphic site has been found in the 3′ untranslated region (UTR) of the human complement component 7 (C7) gene. The polymorphic site at 14-bp downstream from the TAG stop codon was either C or A (Nco I-digested), with allele frequencies of 0.660 and 0.340. This NcoI polymorphism would be useful to perform a DNA marker haplotype study in patients with deficiencies of the complement genes, such as C6, C7, C9, which are located closely on chromosome 5p13.
Similar content being viewed by others
Article PDF
Author information
Authors and Affiliations
Additional information
Received: March 25, 1999 / Accepted: April 3, 1999
Rights and permissions
About this article
Cite this article
Horiuchi, T., Nishizaka, H., Tsukamoto, H. et al. An NcoI polymorphism in the human complement component 7 (C7) gene. J Hum Genet 44, 270–271 (1999). https://doi.org/10.1007/s100380050159
Published:
Issue Date:
DOI: https://doi.org/10.1007/s100380050159