Abstract
FR225654, a novel gluconeogenesis inhibitor, was isolated from the culture broth of Phoma sp. No. 00144 and purified by adsorptive resin and reverse-phase column chromatography. This compound is a potent inhibitor of gluconeogenesis and is a promising candidate of anti-diabetic agent.
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Ohtsu, Y., Sasamura, H., Tanaka, M. et al. The Novel Gluconeogenesis Inhibitor FR225654 that Originates from Phoma sp. No. 00144. J Antibiot 58, 447–451 (2005). https://doi.org/10.1038/ja.2005.58
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DOI: https://doi.org/10.1038/ja.2005.58
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