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Hemospermia: long-term outcome in 165 patients


Long-term course of hemospermia has not been addressed in the sexual medicine literature. We report our 15 years’ experience. From 1997 to 2012, 165 patients presented with hemospermia. Mean age was 38 years. Mean follow-up was 83 months. Laboratory evaluation and testis and transabdominal ultrasonography was done in all. Since 2008, all sonographies were done by the first author. One patient had urinary tuberculosis, one had bladder tumor and three had benign lesions at verumontanum. One patient had bilateral partial ejaculatory duct obstruction by stones. All six patients had persistent, frequently recurring or high-volume hemospermia. All pathologies were found in young patients. In the remaining 159 patients (96%), empiric treatment was given with a fluoroquinolone (Ciprofloxacin) plus an nonsteroidal anti-inflammatory drug (Celecoxib). In our 15 years of follow-up, no patient later developed life-threatening disease. Diagnostic evaluation of hemospermia is not worthwhile in the absolute majority of cases. Advanced age makes no difference. Only high-risk patients need to be evaluated. The vast majority of cases may be safely and effectively treated with empiric therapy. Almost all patients do well in long term.

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  1. Hasegawa T, Shimomura T, Yamada H, Ito H, Kato N, Hasegawa N et al. [Fatal septic shock caused by transrectal needle biopsy of the prostate; a case report]. [Article in Japanese]. Kansenshogaku Zasshi 2002; 76: 893–897.

    Article  Google Scholar 

  2. Han M, Brannigan RE, Antenor JA, Roehl KA, Catalona WJ . Association of hemospermia with prostate cancer. J Urol 2004; 172: 2189–2192.

    Article  Google Scholar 

  3. Mahmud SM . Re: association of hemospermia with prostate cancer. J Urol 2005; 174: 789.

    Article  Google Scholar 

  4. Maheshkumar P, Otite U, Gordon S, Berney DM, Nargund VH . Testicular tumor presenting as hematospermia. J Urol 2001; 165: 188.

    Article  CAS  Google Scholar 

  5. Vilandt J, Sønksen J, Mikines K, Torp-Pedersen S, Colstrup H . Seminoma in the testes associated with haemospermia. BJU Int 2002; 89: 633.

    Article  CAS  Google Scholar 

  6. Leocádio DE, Stein BS . Hemospermia: etiological and management considerations. Int Urol Nephrol 2009; 41: 77–83.

    Article  Google Scholar 

  7. Ahmad I, Krishna NS . Hemospermia. J Urol 2007; 177: 1653–1658.

    Google Scholar 

  8. Stefanovic KB, Gregg PC, Soung M . Evaluation and treatment of hemospermia. Am Fam Physician 2009; 80: 1421–1427.

    PubMed  Google Scholar 

  9. Polito M, Giannubilo W, d'Anzeo G, Muzzonigro G . Hemospermia: diagnosis and treatment. Arch Ital Urol Androl 2006; 78: 82–85.

    PubMed  Google Scholar 

  10. Torigian DA, Ramchandani P . Hemospermia: imaging findings. Abdom Imaging 2007; 32: 29–49.

    Article  CAS  Google Scholar 

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This work was done to commemorate the shining memory and the 58th birthday of Hayaat Zargooshi (1 Ordibehesht 1334–2 Sharivar 1357; 22 April 1955–2 August 1978). Mozhgaan, Newshaa, Aatoosaa and Arya provided assistance.

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Correspondence to S Bidhendi.

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Zargooshi, J., Nourizad, S., Vaziri, S. et al. Hemospermia: long-term outcome in 165 patients. Int J Impot Res 26, 83–86 (2014).

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  • genital diseases
  • hemorrhage
  • hemospermia
  • male
  • semen

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