Clinical Study | Published:

Topical cyclosporin A in the management of vernal keratoconjunctivitis


Purpose To study the efficacy of topical cyclosporin A in children with vernal keratoconjunctivitis in a prospective randomised double-masked trial.

Methods Twenty-four children between 5 and 16 years of age were randomly treated with cyclosporin A (CsA) and placebo (vehicle) and followed up for 4 months.

Results Of the 12 patients given CsA, 11 showed symptomatic improvement by 7 days of starting treatment whereas only 3 patients in the placebo group showed mild symptomatic improvement.

Conclusions Topical cyclosporin is a safe and effective treatment in vernal keratoconjunctivitis.


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Correspondence to Viney Gupta.

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About this article


  • India
  • Placebo-controlled trial
  • Topical cyclosporin
  • Vernal keratoconjunctivitis

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