Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Orbital disease in herpes zoster ophthalmicus

Abstract

Three cases of orbital inflammatory disease caused by herpes zoster are described. This extremely rare complication occurred between 5 days and 14 days following the skin eruption and slowly resolved with or without treatment. Biopsy of a chronic inflammatory lesion on the cheek of one patient demonstrated a sterile vasculitis and granulomatous Iiponecrosis, a process which may underlie the orbital disease in these patients.

References

  1. 1

    Burgoon CF, Burgoon JS, Baldridge GD . The natural history of herpes zoster ophthalmicus. JAMA 1957;75:193–6.

    Google Scholar 

  2. 2

    Edgerton AE . Herpes zoster ophthalmicus. Arch Ophthalmol 1945;93:40–114.

    Article  Google Scholar 

  3. 3

    de Moragas JM, Kierland RR . The outcome of patients with herpes zoster ophthalmicus. Arch Dermatol 1957;75:193–6.

    CAS  Article  Google Scholar 

  4. 4

    Worster-Drought C . Herpes zoster with localised muscular paralysis. BMJ 1923;1:970.

    CAS  Article  Google Scholar 

  5. 5

    Glyn C, Crockford, Gavaghan D . Epidemiology of shingles. J R Soc Med 1990;83:617–9.

    Article  Google Scholar 

  6. 6

    Marsh RJ, Cooper M . Ophthalmic herpes zoster. Eye 1993;7:350–70.

    Article  Google Scholar 

  7. 7

    Womack LW, Liesegang TJ . Complications of herpes zoster ophthalmicus. Arch Ophthalmol 1983;101:42–5.

    CAS  Article  Google Scholar 

  8. 8

    Harding SP, Lipton JR, Wells JCD . Natural history of herpes zoster ophthalmicus: predictors of post-herpetic neuralgia and ocular involvement. Br J Ophthalmol 1987;71:353–8.

    CAS  Article  Google Scholar 

  9. 9

    Scheie HG . Herpes zoster ophthalmicus. Trans Ophthalmol Soc UK 1970;90:899–937.

    CAS  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Geoffrey E Rose.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Vardy, S., Rose, G. Orbital disease in herpes zoster ophthalmicus. Eye 8, 577–579 (1994). https://doi.org/10.1038/eye.1994.140

Download citation

Keywords

  • Herpes zoster ophthalmicus
  • Lipogranuloma
  • Orbital inflammation

Search

Quick links