Abstract
Forty patients with retinal vein occlusion were studied to investigate possible mechanisms leading to an acute rise in intraocular pressure. A rise in intraocular pressure on recumbency was found in 64% of eyes with a central retinal vein occlusion and 65% of eyes with a branch retinal vein occlusion. This finding correlated with glucose tolerance test score, and may be the result of abnormal glucose tolerance in these patients.
Following provocative testing using pilocarpine and phenylephrine, no eye showed irido-corneal contact or angle closure, however over 50% of eyes release pigment into the anterior chamber. Fifty-two per cent of central retinal vein occlusion and 71% of branch retinal vein occlusion eyes that released pigment showed a rise in intraocular pressure.
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Hayreh SS : Central retinal vein occlusion. In Mausolf FA ed. The eye in systemic disease. CV Mosby, St Louis, 1980.
Sanders MD and Graham EM : Medical ophthalmology. In Davidson SI ed. Recent Advances in Opthalmology No. 6, Churchill Livingstone Edinburgh 1983.
Paton A, Rubenstein K, Smith VH : Arterial insufficiency in retinal venous occlusion. Trans Ophthalmol Soc UK 1964, 66: 559–86.
Hayreh SS, van Heuven AJ, Hayreh MS : Experimental retinal vascular occlusion. 1. Pathogenesis of central retinal vein occlusion. Arch Ophthalmol 1978, 96: 311–23.
Vannas S and Tarkkanen A : Retinal vein occlusion and glaucoma. Tonographic study of the incidence of glaucoma and of its prognostic significance. Br J Opthalmol 1960, 44: 583–9.
Fontana ST and Brubaker RF : Volume and depth of the anterior chamber in the normal aging human eye. Arch Ophthalmol 1980, 98: 1803–8.
Aggarwal JL and Beveridge B : Liberation of the iris pigment in the anterior chamber. Br J Opthalmol 1971, 55: 544–9.
Mapstone R : Pigment release. Br J Ophthalmol 1981, 65: 258–63.
Williams BI and Peart WS : Retinal vein obstruction and intraocualr pressure: abnormal postural response independent of facility of outflow. Br J Opthamol 1979, 63: 805–7.
Schenker HI, Luntz MH, Kelsb, et al: Exercise induced increase of intraocular pressure in the pigmentary dispersion syndrome. Am J Ophthalmol 1980, 89: 598–600.
Epstein DL, Boger WP, Grant WM : Phenylephrine provocative testing in the pigmentary dispersion syndrome. Am J Ophthalmol 1978, 85: 43–50.
Hayreh SS, March W, Phelps CD : Ocular hypotony after retinal vascular occlusion. Tr Ophthalmol Soc UK 1977, 97: 757–67.
Anomalous postural response of intraocular pressure in vascular disease (Editorial). Lancet 1981, i: 314.
Williams BI and Peart WS : Effect of posture on the intraocular pressure of patients with retinal vein occlusion. Br J Ophthalmol 1978, 62: 688–93.
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Ansons, A., Clearkin, L. & Bryce, I. Mechanisms leading to an acute rise in intraocular pressure in retinal vein occlusion. Eye 4, 439–444 (1990). https://doi.org/10.1038/eye.1990.55
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DOI: https://doi.org/10.1038/eye.1990.55