The clinical significance of the tumor immune microenvironment is well established – in particular, the role of tumor-infiltrating lymphocytes (TILs), which can act as predictive and prognostic biomarkers in a range of solid tumors.
Spatial omics techniques such as multiplex immunofluorescence, fluorescence in situ hybridization, and imaging mass cytometry have added to knowledge about how the spatial architecture of many solid cancers and their microenvironments can impact clinical prognosis and response to treatments. However, the feasibility of applying such analysis in routine clinical diagnosis remains a challenge.
This webcast will describe discoveries made using spatial omics in breast cancer and metastasis to the brain, the application of such analyses on retrospective cohorts to predict patient outcomes, and some of the challenges that arise in applying these technologies to clinical practice, such as in routine biopsies.
Learn about:
• Complexity of the tumor immune system, not limited to T cells and macrophages
• How spatial characterization of the tumor immune landscape of cancer is predictive of patient outcome
• How we can use spatial-omics technologies to predict patient response to therapy and outcomes
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This webcast has been produced by ZEISS Microscopy, who retails sole responsibility for content. About this content.
Speaker
Morag Park, Director, Rosalind and Morris Goodman Cancer Institute, McGill University
Morag Park, PhD, C.Q. FRSC, FCAHS, is a Professor in the Departments of Biochemistry, Medicine and Oncology at McGill University. She is the Director of the Rosalind and Morris Goodman Cancer Research Centre and has served as the Scientific Director of the CIHR Institute of Cancer Research, and Director of McGill Molecular Oncology Group.
Moderator
Sarah Hiddleston, Nature Research Custom Media
Sarah Hiddleston is a freelance journalist who has worked with Nature Research Custom Media since 2015. Previously, Sarah worked for a decade in Madras (Chennai), India, specialising in health, pharmaceutical and environmental stories. Sarah holds an MA in Investigative Journalism from City University London, an MSc in Political Theory from the London School of Economics, and an undergraduate degree in History from the University of Cambridge, UK.
