There is an increasing demand for whole genome sequencing (WGS), but cost is still a barrier for small-scale projects. To bring WGS to broader clinical use, efforts have been undertaken to further reduce cost and turnaround time while improving sequencing performance.
This webcast will highlight how to accomplish completely PCR-free WGS – in which the whole process is not only PCR-free during library preparation, but also PCR-free during sequencing – via the DNBSEQ platform.
Leveraging the no clonal error rate of DNA NanoBall (DNB)-based sequencing technology and the high signal density of patterned nanoarray chips, DNBSEQ has high performance in applications such as WGS and whole exome sequencing. This process offers multiple advantages, including increased accuracy, decreased duplicates, and no index hopping.
Learn about:
• Achieving PCR free-WGS on the DNBSEQ sequencing platforms
• How single tube long fragment reads (stLFR) enables synthetic long reads with DNBSEQ
• How these technologies are helping to move WGS into a new era of broad clinical use
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This webcast has been produced by Complete Genomics Inc., who retails sole responsibility for content. About this content.
Speaker
Rade Drmanac, Chief Scientific Officer, Complete Genomics
Radoje (Rade) Drmanac, PhD, chief scientific officer and co-founder of Complete Genomics Inc., is a research scientist and inventor in the field of human genome sequencing including techniques such as DNA sequencing-by-hybridization (SBH), genomic micro- and nanoarrays, combinatorial probe ligation, and the long fragment read (LFR) process for accurate whole genome sequencing and haplotyping from 10 human cells. Rade was a group leader at Argonne National Labs from 1991 to 1994 as part of the Department of Energy’s Human Genome Project.
Moderator
Sarah Hiddleston, Nature Research Custom Media
Sarah Hiddleston is a freelance journalist who has worked with Nature Research Custom Media since 2015. Previously, Sarah worked for a decade in Madras (Chennai), India, specialising in health, pharmaceutical and environmental stories. Sarah holds an MA in Investigative Journalism from City University London, an MSc in Political Theory from the London School of Economics, and an undergraduate degree in History from the University of Cambridge, UK.