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Gene expression and epigenetic regulation co-mapped in brain tissues

Gene expression and features of the DNA–protein complex chromatin were mapped together at high spatial resolution in tissue sections of the mouse or human brain. This spatially resolved technology enables the examination of the spatio-temporal dynamics and regulation of gene expression in complex mammalian tissues.

This is a summary of: Zhang, D et al. Spatial epigenome–transcriptome co-profiling of mammalian tissues. Nature https://doi.org/10.1038/s41586-023-05795-1 (2023).

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doi: https://doi.org/10.1038/d41586-023-00436-z

‘Expert opinion’ and the figure are published under a CC BY 4.0 licence.

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