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How a tiny genetic change inflicts old age on young kids

A composite of six images showing Masson-stained oesophagi derived from mice.

Mice with a version of the disease progeria have abnormal oesophagi (middle, top; detail middle, bottom). Mice treated with a newly developed molecule have oesophagi (right) similar to those of mice without the condition (left). Credit: N. Zhang et al./Nature Aging (CC BY 4.0)

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Nature 614, 392 (2023)


Updates & Corrections

  • Correction 15 February 2023: An earlier version of the caption accompanying this article misidentified the pictured tissue.


  1. Zhang, N. et al. Nature Aging (2023).

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