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  • RESEARCH HIGHLIGHT

Link between brain atrophy and the microbiome emerges in mice

Changes similar to those seen in Alzheimer’s disease are less pronounced in mice with minimal levels of gut bacteria.
Coloured transmission electron micrograph of a neuron in Alzheimer's disease

Tau-protein fibres (stacks of green filaments) are prominent in a neuron of a person with Alzheimer’s disease. Credit: Thomas Deerinck, NCMIR/Science Photo Library

Research on mice suggests that the gut microbiome plays a part in the development of Alzheimer’s disease1.

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Nature 613, 417 (2023)

doi: https://doi.org/10.1038/d41586-023-00038-9

References

  1. Seo, D.-O. et al. Science 379, eadd1236 (2023).

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