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Caption: Variety of fresh green vegetables.

A species of bacterium in the human gut helps to bestow cancer-fighting abilities on members of the Brassica family such as broccoli and cabbage (seen here with other vegetables). Credit: Getty

Microbiome

How gut bacteria make broccoli a superfood

Scientists reveal the pathway used by one gut microbe to transform vegetable components into anti-cancer compounds.

Broccoli — the poster child for vegetable hatred — has been rehabilitated recently thanks to its link to cancer prevention. Now researchers have revealed how a common gut microbe helps the body to take advantage of the health benefits of this and related foods.

Broccoli, cabbage, cauliflower and other vegetables in the Brassica genus owe their distinctive flavour to chemicals known as glucosinolates. During digestion, gut bacteria transform glucosinolates into compounds called isothiocyanates, which have protective effects against certain cancers.

Elizabeth Sattely at Stanford University in California and her colleagues pinpointed a set of genes that gives the gut microbe Bacteroides thetaiotaomicron the ability to turn glucosinolates into isothiocyanates. Mice colonized with B. thetaiotaomicron bacteria that lacked a complete set of these genes had lower levels of isothiocyanates in their digestive tract than did mice colonized with typical B. thetaiotaomicron. And when the researchers introduced the genes into bacteria that do not normally help to digest glucosinolates, the microbes began producing isothiocyanates.

Knowledge of this microbial mechanism could help efforts to engineer microbes to prevent and treat human disease, the authors say.

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Ocean sciences

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Quantum information

Quantum keys dial up tamper-proof conference calls

A new experiment efficiently distributes the highly secure keys to four parties instead of the typical two.
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Workers harvest pineapples in Lingao County, China. Less than one-third of the money spent on food eaten at home reaches farmers. Credit: Yuan Chen/VCG/Getty

Economics

Poor harvest: farmers earn a pitiful fraction of the money spent on food

The bulk of consumer food spending around the world ends up in the coffers of distributors, processors and other parties beyond the farm gate.
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A pedestrian seeks relief from searing temperatures in Spain, where a high proportion of heat-related deaths have been linked to climate change. Credit: SALAS/EPA-EFE/Shutterstock

Climate change

More than one-third of heat deaths blamed on climate change

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