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Reproducibility trial publishes two conclusions for one paper

The British Journal of Anaesthesia’s unusual experiment is designed to broaden replicability efforts beyond just methods and results.
  1. David Adam
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How deeply an anaesthetist should sedate an elderly person when they have surgery is a controversial issue, because some studies link stronger doses of anaesthetic with earlier deaths. So it should reassure clinicians to see a study1 in the British Journal of Anaesthesia that investigates and rules out such a link — the published paper’s discussion section says so explicitly: “These results are reassuring.”

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Nature 570, 16 (2019)

doi: https://doi.org/10.1038/d41586-019-01751-0

References

  1. Sieber, F. et al. Br. J. Anaesthesiol. 122, 480–489 (2019).

    Article  PubMed  Google Scholar 

  2. Vlisides, P. E., Ioannidis, J. P. A. & Avidan, M. S. Br. J. Anaesthesiol. 122, 421–427 (2019).

    Article  PubMed  Google Scholar 

  3. Avidan, M. S., Ioannidis, J. P. A. & Mashour, G. A. Br. J. Anaesthesiol. 122, 413–420 (2019).

    Article  PubMed  Google Scholar 

  4. Sneyd, J. R. Br. J. Anaesthesiol. 122, 407–408 (2019).

    Article  PubMed  Google Scholar 

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